Table of Contents

Original Research Article(continued)

1. Article

   Inhibitory Effect of Cayratia albifolia C. L. Li Extract on LPS-induced Inflammation of RAW264.7 Cells by Regulating the Nrf2/ HO-1 Axis

   Yi Tan, Liang Cao, Dan Zhou, Biao Qin, Yanbin Zhang, Jianxin Liu, Kai He, Bin Li, Zaiqi Zhang

   pp. 207–217 · DOI: 10.1177/09731296241266095 · 2025

   Background: Cayratia albifolia C. L. Li (Jiao Mei Gu (JMG)) has potential therapeutic effects in inflammatory diseases. Objectives: The primary goal of the research was to focus on the antioxidant and anti-inflammatory q…

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2. Article

   Wogonin Alleviates Streptozotocin-stimulated Diabetic Nephropathy through its Antidiabetic, Antidyslipidemic, and Antioxidative Effects in Rats

   Dong Li, Hui Li, Buchao Shi, Changhong Li

   pp. 218–228 · DOI: 10.1177/09731296241274880 · 2025

   Background: Diabetes mellitus (DM) is a prolonged endocrine syndrome recognized by defective metabolism of biomolecules on account of flaws in insulin resistance. Diabetic nephropathy (DN) is a central microvascular comp…

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3. Article

   Investigation of Cytotoxicity and Lipid-lowering Effects of Rivea hypocrateriformis Desr. Leaf Extracts on HepG2 Cells: An in vitro Study

   Helen Sheeba Devadhasan Aspathi Bai, Gandhimathi Rethnaswamy

   pp. 229–242 · DOI: 10.1177/09731296241263660 · 2025

   Background and Purpose: Chronic diseases, such as cardiovascular disease as well as type 2 diabetes, are associated with hyperlipidemia, characterized by high blood lipid levels. HepG2 cells, a human liver cancer cell li…

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4. Article

   Aucubin Induces Apoptotic Cell Death Through Caspase-dependent Pathways in Human Osteosarcoma MG-63 Cells

   Mengfan Cui, Pengyu Chen

   pp. 243–255 · DOI: 10.1177/09731296241277314 · 2025

   Background: Osteosarcomas (OSs) are predominantly generated by mesenchymal cells, which commonly develop in the distal and upper regions of the bones. OS has high mortality rates and treatment failures, mostly due to the…

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5. Article

   Protective Role of Anthraquinone Purpurin Against Cardiotoxicity Induced by Isoproterenol in Adult Wistar Rats

   Xuecai Wang, Yaguo Huang, Xiaojuan Sun, Bing Zhao

   pp. 256–268 · DOI: 10.1177/09731296241281446 · 2025

   Background: Purpurin are naturally occurring anthraquinones derived from the roots of Rubia species. Purpurin is a redcolored bioactive compound commonly used as a food colorant. In ancient times, Rubia species plants we…

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6. Article

   Attenuation of L-NAME-induced Hypertension in Rats with Elettaria cardamomum–Low-dose Amlodipine Combination: A Possible Synergism of Covasodilatory Effect

   Abdulaziz K. Al Mouslem, Dimah I. Almuayli, Sara M. Aldaej, Zainab A. Alhaddad, Fatimah J. Alhamad, Promise M. Emeka, Enas S. Gad

   pp. 269–281 · DOI: 10.1177/09731296241278035 · 2025

   Background: Hypertension is a prevalent chronic disorder that affects approximately 1.28 billion adults worldwide. In the use of amlodipine, though it is a cost-effective antihypertensive agent, it causes side effect tha…

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7. Article

   Ameliorative Potency of Iridoid Glucoside Compound Catalpol on Inhibiting NF-κB-mediated Inflammation in Allergic Rhinitis-induced Mice

   Haiting Wang, Jing Wang

   pp. 282–292 · DOI: 10.1177/09731296241281429 · 2025

   Background: Over time, the prevalence of allergic rhinitis (AR) has surged due to various risk factors, notably attributed to global urbanization, rendering heightened levels of pollutants, including traffic-related emis…

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8. Article

   The Extract of Camellia japonica L. Protects against Mice Cerebral Ischemia/Reperfusion Injury via Promoting the H2S-BKCa Pathway

   Weizhuo Lu, Zenghong Jiang, Jiyue Wen

   pp. 293–304 · DOI: 10.1177/09731296241265738 · 2025

   Background and Objectives: The effect and mechanism of the extract of Camellia japonica L. (ECJ) on brain injury following cerebral ischemia/reperfusion (I/R) were demonstrated in the present study. Materials and Methods…

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9. Article

   Green Synthesis of Chitosan-coated Tin Dioxide Nanoparticles Using Moringa oleifera Flower Extract Against Breast Cancer via the Caspase-dependent Apoptotic Pathway

   Ahmad Alsulimani, Saleh M. Abdullah, Ahmed Ali Jerah, Ali M. Hendi, Abdullah Farasani

   pp. 305–314 · DOI: 10.1177/09731296241276588 · 2025

   Background and Purpose: In the present work, chitosan is furnished with tin dioxide (CsSnO2) nanoparticles (NPs) synthesized using the green route using Moringa oleifera (M. oleifera) flower extract. Materials and Method…

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