Table of Contents

Original Research Article(continued)

1. Article

   Quercetin Suppresses Gastric Cancer Progression Through Inhibition of Cell Proliferation, Migration, and Tumor Growth

   Zhonghua Wu, Wu Xie

   pp. 1457–1463 · DOI: 10.1177/09731296261436883 · 2026

   Background and Objectives: Quercetin, a widely distributed flavonoid in medicinal plants, exhibits potent anti-cancer effects across various malignancies. However, its pharmacological activity in gastric cancer remains i…

   TextPDFLens
2. Article

   Protective Role of Corosolic Acid Against the Ovalbumin-induced Allergic Rhinitis in Mice Through the Suppression of Inflammatory Response

   Dandan Su, Qian Zheng, Qiang Wang

   pp. 1464–1472 · DOI: 10.1177/09731296261446135 · 2026

   Background: Allergic rhinitis, a worldwide health issue, is defined by immunoglobulin E (IgE)-mediated inflammation of nasal mucosa, resulting in symptoms like sneezing and nasal obstruction. The increasing incidence of …

   TextPDFLens
3. Article

   Amarogentin Inhibits Cell Viability and Promotes Apoptosis in Breast Cancer MDA-MB-231 Cells via Increasing Oxidative Stress and Inhibiting PI3K/AKT/mTOR Pathway

   Minxiang Wei, Yujie Gu, Cuiyu Han, Yuanyuan Liu, Lu Yan, Rui Gao

   pp. 1473–1480 · DOI: 10.1177/09731296261444835 · 2026

   Background: Breast cancer is the most common cancer type in women globally, constituting a substantial portion of all documented female malignancies. It is the second major cause of cancer-associated mortality in women, …

   TextPDFLens
4. Article

   Chrysoeriol Inhibits Viability and Triggers Caspase-dependent Apoptosis in Thyroid Cancer TPC-1 Cells

   Xi Dong, Xiaodong Li, Shuheng Li, Weiying Ge, Na Feng

   pp. 1481–1496 · DOI: 10.1177/09731296261444852 · 2026

   Background: Thyroid cancer represents the most prevalent endocrine cancer, with papillary thyroid carcinoma responsible for the most cases and presenting a significant clinical challenge due to its variable prognosis. Ob…

   TextPDFLens
5. Article

   Preventive Effects of Tomatidine Against Sodium Selenite-induced Oxidative Damage and Cataractogenesis in Rats via Activating Nrf-2 Pathway

   Liang Bai, Shiju Zhu

   pp. 1497–1507 · DOI: 10.1177/09731296261447608 · 2026

   Background: Cataracts, characterized by the gradual opacification of the crystalline lens, represent a primary cause of vision impairment worldwide, placing a considerable burden on individuals and healthcare systems. Un…

   TextPDFLens
6. Article

   Protective Role of Ajmalicine Against Benzo(a)pyrene-induced Lung Cancer Through Regulation of Inflammatory and Oxidative Pathways

   Hongqian Yan, Xiangyan Yu, Yinghao Su, Limei Geng, Yuzhen Pei

   pp. 1508–1518 · DOI: 10.1177/09731296261447607 · 2026

   Background: Lung cancer is a foremost global health challenge and remains the leading cause of cancer-related mortality worldwide. Despite advancements in early diagnosis and treatment, most cases are detected at advance…

   TextPDFLens
7. Article

   Evaluation of the Cardioprotective Potential of Polygala tenuifolia Ethanolic Extract via Antioxidant and Anti-inflammatory Mechanisms in Myocardial Infarction: An In Vivo Study

   Zhen Wu, Mei Zhao

   pp. 1519–1527 · DOI: 10.1177/09731296261446811 · 2026

   Background: Myocardial infarction (MI) continues to be a leading contributor to illness and death worldwide, even in the face of substantial therapeutic and preventive interventions. Polygala tenuifolia, a traditional me…

   TextPDFLens
8. Article

   Commiphora gileadensis Reduces Blood Glucose Levels and HbA1c in Type 2 Diabetic Mice by Inducing Muscular GLUT4

   Ayman Saeed Alhazmi

   pp. 1528–1537 · DOI: 10.1177/09731296261446642 · 2026

   Background: Diabetes mellitus represents a significant health challenge that affects the broader population. A small tree, Commiphora gileadensis (C. gileadensis), is native to the Middle East. Objectives: This research …

   TextPDFLens
9. Article

   Bavachin Mitigates Bone Loss via RANKL Inhibition and Runx2 Activation in a Rat Model of Post-menopausal Osteoporosis

   Chao Shang, Junlai Song, Xiaosong Li

   pp. 1538–1550 · DOI: 10.1177/09731296261447606 · 2026

   Background: Globally, post-menopausal osteoporosis poses a major health challenge, primarily affecting elderly women because of its connection to lowered bone mineral density and increased susceptibility to fractures. Th…

   TextPDFLens
10. Article

    Monoterpene Ketone Piperitone Mitigates Cataractogenesis via Antioxidant Enhancement, Redox Modulation, and Anti-inflammatory Mechanisms in a Selenite-induced Rat Model

    Jianying Sun, Qiaoyan Yin

    pp. 1551–1562 · DOI: 10.1177/09731296261447614 · 2026

    Background: Cataracts remain the foremost cause of preventable blindness globally, with oxidative stress serving as a central contributor to their pathogenesis. Given the limited accessibility of surgical intervention in…

    TextPDFLens
11. Article

    Trans-Ferulic Acid, A Functional Phenolic Compound from Plants, Exerts Cellular Level Cardioprotection in Ischaemic H9c2 Cells by Modulating NRF2 and HIF1α Pathways

    Kai Wang, Xiulan Qiao, Shengling Yan, Nouf Ahmed Tumayhi, Yahya Khaled Mashhour, Abdullah Taher Shami, Abdullah Farasani

    pp. 1563–1574 · DOI: 10.1177/09731296261450312 · 2026

    Background: Ischaemic heart disease (IHD) is currently managed by drugs and minimally invasive procedures. However, the necessity for safe, eco-friendly herbal-based medications is consistently advocated to prevent the s…

    TextPDFLens
12. Article

    Green Synthesized Reduced Graphene Oxide–Silver Nanocomposite as an Effective Anti-bacterial Agent Towards Chronic Suppurative Otitis Media Pathogens

    Lizhu Wang, Yanli Yang, Shuling Li, Biao Ruan

    pp. 1575–1586 · DOI: 10.1177/09731296261450790 · 2026

    Background: Chronic suppurative otitis media (CSOM) is a significant cause of hearing impairment in developing countries and is frequently associated with severe intracranial and extracranial complications. The increasin…

    TextPDFLens
13. Article

    Identification of Comorbid Genes of Psoriasis and Coronary Artery Disease Using Ustekinumab with Astragalus

    Huawei Hu, Yangyang Huang, Xiaolin Xie

    pp. 1587–1596 · DOI: 10.1177/09731296261450762 · 2026

    Background: Systemic inflammation leading to coronary atherosclerotic heart disease (CAD) increases the risk for Psoriasis (PSO). Despite progress in diagnostic and therapeutic strategies for CAD, it is hard to identify …

    TextPDFLens
14. Article

    Neuroprotective Effects of Gigantol on Cerebral Ischemia–Reperfusion Injury in Rats via Regulation of Inflammation, Oxidative Stress, and Apoptotic Mechanisms

    Jing Chen, Liang Ma

    pp. 1597–1607 · DOI: 10.1177/09731296261454095 · 2026

    Background: Cerebral ischemic stroke, a devastating neurological condition, arises from the disruption of blood flow to the brain, resulting in oxygen and nutrient deprivation and subsequent neuronal damage. Ischemic str…

    TextPDFLens
15. Article

    Albiflorin Inhibits Cell Viability and Promotes Apoptosis in Breast Cancer MDA-MB-231 Cells via Regulating Bcl-2 Family Proteins Rui Gao1*

    Chaoyu Bi, Xuerun Du, Minxiang Wei, Minhua Xiao, Lu Yan

    pp. 1608–1616 · DOI: 10.1177/09731296261462393 · 2026

    Background: Breast cancer remains the most widely diagnosed cancer among women worldwide and a major cause of cancer-associated deaths, posing a substantial and escalating burden on public health systems worldwide. Objec…

    TextPDFLens
16. Article

    Rosiridin Attenuates Liver Injury by Modulating Antioxidant Activity and Inflammatory Markers in Thioacetamide-induced Liver Cirrhosis in Experimental Rats

    Ying Chang, Quanwei Di, Shining Lou, Jie Meng, Xinli Feng, Xinwen Zhang

    pp. 1617–1626 · DOI: 10.1177/09731296261462392 · 2026

    Background: Liver cirrhosis, a chronic and progressive liver disease, represents the end-stage of several hepatic injuries, characterized by widespread fibrosis, nodule formation, and ultimately, liver dysfunction and fa…

    TextPDFLens
17. Article

    Formulation and Evaluation of Polyherbal Silver Nanoparticle-loaded Thermosensitive Poloxamer Gel for Acute Wound Healing

    Predeepkumar Narayanappa Shiroorka, Yogesh Kumar S, Sowmya Sowmya, Prakash Goudanavar, Nimbagal Raghavendra Naveen, Vedamurthy Joshi, Girish Meravanige, Krishna Swaroop, Nagaraja Sreeharsha

    pp. 1627–1638 · DOI: 10.1177/09731296261466063 · 2026

    Background: Wound healing is a dynamic, multistage biological process involving hemostasis, inflammation, proliferation, and remodeling. Despite advances in wound care, effective management of acute wounds remains a chal…

    TextPDFLens
18. Article

    α-Hederin Mitigates Streptozotocin-induced Diabetic Nephropathy in Rats via Regulating Physiological Changes, Inflammation, and Oxidative Stress Responses

    Qian Zhang, Limin Zhang, Chenchen Li, Ling Tian, Shanshan Guo, Xuying Liu

    pp. 1639–1650 · DOI: 10.1177/09731296261462768 · 2026

    Background: Diabetic nephropathy, a severe microvascular complication of diabetes, is a primary cause of end-stage renal disease worldwide, significantly contributing to morbidity and mortality. Despite advancements in g…

    TextPDFLens
19. Article

    Gardenin A Alleviates Diabetic Nephropathy by Modulating Oxidative Stress and Inflammation in Experimental Rats

    Juan Ji, Longhai Song, Chong Yang, Yan Gao, Song Li, Qiaoying Wu

    pp. 1651–1660 · DOI: 10.1177/09731296261464762 · 2026

    Background: Diabetic nephropathy is a formidable microvascular complication of diabetes mellitus, considerably contributing to global morbidity and mortality due to its role as the primary factor of end-stage renal disea…

    TextPDFLens
20. Article

    Neuroprotective Effects of Santonin on Aluminum Chloride-induced Oxidative Stress Mediated Neuroinflammation in Rat Model of Alzheimer’s Disease

    Hongxing Xue, Xiaowei Zhu, Haixu Hao

    pp. 1661–1671 · DOI: 10.1177/09731296261466884 · 2026

    Background: Alzheimer’s disease (AD) is one of the neurodegenerative diseases that is marked by deterioration in cognitive functioning and behavioral capacities in a progressive manner. It is the most prevalent cause of …

    TextPDFLens