Table of Contents

Original Research Article(continued)

1. Article

   Mechanisms of Salidroside in Treating Premature Ovarian Insufficiency: Network Pharmacology and Molecular Docking

   Lili Wei, Baoman Ma, Dan Wu, Le Wang, Xueting He, Ying Gong, Chujuan Lin

   pp. 1028–1039 · DOI: 10.1177/09731296251367162 · 2026

   Background: Salidroside has multiple functions such as antiinflammatory, neuroprotection, immunomodulation, antioxidative stress, and antiapoptosis. However, its application in the treatment of ovarian insufficiency is n…

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2. Article

   Impact of Lonicera japonica Extract on Nerve Growth Factor and Inflammatory Pathways in a Mouse Modeling of Allergic Rhinitis

   Zhifeng Deng, Ting Zhu, Xiaoting Tong, Wendan Shi, Yu Xu, Minli Zhang

   pp. 1040–1055 · DOI: 10.1177/09731296251355171 · 2026

   Background: Although Lonicera japonica extract (LJE) has been widely used in traditional medicine for treating conditions such as heat-clearing, detoxification, and anti-bacterial purposes, its specific effects on allerg…

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3. Article

   Hesperidin Recovers Lipopolysaccharideinduced Preeclampsia-like Complications in Pregnant Rat Model

   Jing Zhou, Yang Yang, Xinxin Liang

   pp. 1056–1065 · DOI: 10.1177/09731296251364997 · 2026

   Background: Preeclampsia is a complex and multifactorial disorder that develops during pregnancy, defined by the onset of hypertension and proteinuria, often accompanied by other systemic manifestations. Objectives: The …

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4. Article

   Investigation of Ameliorative Effects of Black Rice and Purple Sweet Potato Extracts-rich Anthocyanins Against Animal Model of Insulin Resistance and Type 2 Diabetes

   Suhas Dhondibhau Tambe, P. Sivakami Sundari, Geetha Kannoth Mukundan

   pp. 1066–1075 · DOI: 10.1177/09731296251384042 · 2026

   Background: Nutraceuticals are popular because of a wide variety of biological actions, largely because of the contents present like alkaloids, glycosides, terpenoids, oils, tannins and several other phytochemicals. Anth…

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5. Article

   Investigating the Potential Targets and Mechanisms of Action of Chinese Medicine for the Treatment of EIV Based on Network Pharmacology and Molecular Docking as Well as in vitro

   Nannan Chen, Jiewei Wang, He Han, Liang Chen, Bochao Liu, Shuang Wang, Yu Liu, Pingwei Qin

   pp. 1076–1092 · DOI: 10.1177/09731296251371462 · 2026

   Background: Equine influenza virus (EIV) can cause acute infections and outbreaks of epidemics in horses and donkeys. It is one of the most economically impactful pathogens in equine respiratory diseases globally, result…

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6. Article

   Inhibition of Oral Carcinoma Cell Proliferation by miR-15b Carrying Pterostilbene and Related Mechanisms

   Ting Du, Ting Hao, Qiaoyun Shi

   pp. 1093–1100 · DOI: 10.1177/09731296251371466 · 2026

   Background: MicroRNA-15b (miR-15b) plays a cancer-suppressing role in various tumors, while sandalwood astragalus, as a natural antioxidant, has significant anti-cancer potential. However, the synergistic mechanism of mi…

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7. Article

   Curcumin Promotes Mitochondrial Apoptosis of Cancer-derived Lung Cancer Stem Cells and Cisplatin Sensitization Through BH3-only Dephosphorylation

   Zhigang Lu, Chunlin Li, Jiayang Sun

   pp. 1101–1108 · DOI: 10.1177/09731296251367935 · 2026

   Background: Lung cancer’s mortality ranks first among other cancers. Several studies have shown the role of microRNAs in the pathogenesis of lung cancer. Objectives: This study investigates microRNA-1297’s (miR-1297) rol…

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8. Article

   Surface Polyethylene Glycol Nanoliposomeencapsulated microRNA-495-3p Regulates mTOR Pathway and Improves Immune Cell Function in Colon Cancer Through Targeting GXYLT1

   Lingqing Cai, Jiangrong Chen, Chuanqing Ke, Baiping Zhang, Yuqing Xiong, Huiying Fu

   pp. 1109–1117 · DOI: 10.1177/09731296251371482 · 2026

   Background: miR-495-3p expression is related to tumor pathogenesis. Objectives: This study explores the mechanism of the protective role of miR-495-3p in colon cancer and its interaction with glucoside xylosyltransferase…

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9. Article

   Effect of Curcumin-loaded Polystyrene Nanoparticles on Inhibiting the Generation of Lymphatic Vessels in Gastric Cancer Nude Mice Under Hypoxic Microenvironment

   Yanjin Long, Xin Kang, Bin Li, Tiansheng Yin, Yajun Zhang

   pp. 1118–1126 · DOI: 10.1177/09731296251371477 · 2026

   Background: In the treatment of gastric cancer, lymphangiogenesis under a hypoxic microenvironment has always been a current research hotspot. Objectives: This study aimed to explore the mechanism of curcumin-loaded poly…

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10. Article

    Antioxidant Potential and Flavonoid Marker Detection in Two Ficus carica Linn. Varieties

    Hamda Al Jabri, Shaik Nyamathulla, Najihah Mohd Hashim, Lip Yong Chung

    pp. 1127–1138 · DOI: 10.1177/09731296251391607 · 2026

    Background: Studying the antioxidant properties of various plants used in alternative medicine can support evidence-based medicine practice. Objectives: This investigation delves into the chemical composition and antioxi…

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11. Article

    Mechanism of Cucurbitacin’s Inhibition of Autophagy in Lung Cancer and Its Study in Magnetic Nano Piggyback System

    Zhifei Zhao, Meng Yu, Wenfu Shi, Tao Zhang

    pp. 1139–1149 · DOI: 10.1177/09731296251371926 · 2026

    Background: The mortality rate of lung cancer is increasing. Ferric oxide nanoparticles are magnetic and biocompatible nanomedicines. Cucurbitacin has anti-tumor activity. Its pharmacological effects and molecular mechan…

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12. Article

    Schizonepeta tenuifolia Formula: Anti-hemorrhoid Activity via Antiangiogenesis in Hemorrhoid Rats

    Chao Gu, Yu Xue, Jiayu Bi, Xiaohua Li, Zheng Liu

    pp. 1150–1158 · DOI: 10.1177/09731296251371924 · 2026

    Background: Hemorrhoids are a prevalent condition characterized by anal vein dilation and prominent vascular hyperplasia, accompanied by symptoms such as rectal bleeding, itching, and discomfort. Currently, the conventio…

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13. Article

    Polystyrene Targeting Nanoparticles’ Effect on Lung Injury in Severe Acute Pancreatitis

    Ming Chen, Zhe Wu, Yiqin Yu, Jinhong Wang

    pp. 1159–1165 · DOI: 10.1177/09731296251380005 · 2026

    Background: Severe acute pancreatitis (SAP) has an acute onset and critical condition. It can mainly cause a pulmonary infection in patients. Whether polystyrene targeting nanoparticles play a role in lung injury in SAP …

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14. Article

    Neuropeptide Y3-36-loaded PVAX Nanoparticles Enhance Angiogenesis in Myocardial Ischemia

    Jiao Liu, Qing Li, Lini Zhao

    pp. 1166–1173 · DOI: 10.1177/09731296251367547 · 2026

    Background: Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter widely found in the heart, as it affects cardiac function. Objectives: This study aimed to explore the effect of PVAX nanoparticles carrying NPY3…

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15. Article

    Pharmacognostical Studies and Validation of Polyphenol Rich Extract of Alectra parasitica subsp. chitrakutensis in Traditional Claim for Edema

    Adarsh Tiwari, Vairavan Ramesh, Mridul Kant Chaudhary, Manoj Tripathi, Ankita Misra, Sharad Srivastava

    pp. 1174–1180 · DOI: 10.1177/09731296251403799 · 2026

    Background: Alectra parasitica subsp. chitrakutensis, a holoparasitic plant endemic to India, is traditionally used for rheumatism, edema, and leukoderma. However, scientific validation of its medicinal claims remains li…

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16. Article

    Study on the Mechanism of Berberine Based on PI3K/mTOR/Autophagy Pathway to Ameliorate Sepsis-associated Encephalopathy Injury

    Yu Li, Wei Du, Shijun Tang, Yuan-Jia Yue, Xing Rong, Hongxiang Wang, Dugujia Gaerma, Lin Jiang

    pp. 1181–1187 · DOI: 10.1177/09731296251384399 · 2026

    Background: Sepsis-associated encephalopathy (SAE) is a major cause of high mortality, and no specific therapeutic drugs are currently available. Berberine has been well-documented for its neuroprotective effects, but it…

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17. Article

    Effect of Baicalein Inhibiting miR-155 through STAT3 Signaling Pathway on Inflammatory Response in Mice with Acute Appendicitis

    Yunyun Hu, Longfei Zhao, Ruidong Chen, Han Xu, Hong Li

    pp. 1188–1199 · DOI: 10.1177/09731296251375227 · 2026

    Background: Acute appendicitis is caused by infection and inflammation of the appendix. Baicalein (ABC) can reduce inflammation through various mechanisms, but its water solubility is poor. Liposomes have good biocompati…

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18. Article

    Effects of Resveratrol on Cardiomyocyte Hypoxia-reoxygenation Injury Induced by High Glucose and Its Relationship with NRG1/ErbB Pathway

    Mingyang Wang, Dai Dai, Jian Li, Xiaolin Zhang, Zhengyu Hao, Fanxi Kong, Jing Zhang

    pp. 1200–1212 · DOI: 10.1177/09731296251385377 · 2026

    Background: Research has found that diabetes and cardiomyopathy are partially caused by hypoxia-reoxygenation damage to myocardial cells in a high-glucose environment. Resveratrol (RSV) exhibits protective effects on the…

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19. Article

    Comprehensive Review of Fritillaria: Medicinal History, Botanical Sources, Geographical Distribution, Extraction and Isolation Methods, and Anti-lung Cancer Activity

    Jiangfan Yu, Chunzheng Ma, Denghui Shi, Jiarui Cao, Shasha Cao

    pp. 1213–1222 · DOI: 10.1177/09731296251382016 · 2026

    Background: The Fritillaria genus has been widely employed in traditional Chinese medicine (TCM) for thousands of years as an expectorant and cough suppressant. The primary active components in *Fritillaria* are alkaloid…

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